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顺序:人Tim-4(氨基酸25~315)胞外结构域融合在人IgG1 Fc区域的N端。
作用物种:人。
生物活性:抑制CD3抗体诱导的刺激性T细胞的增殖。
内毒素含量:<0.06EU/μg蛋白 (LAL测试; Lonza)。
重悬:100ul灭菌水。1×PBS稀释到需要的浓度。
形态:粉末,0.2uM过滤的PBS溶液。
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文献和实验Quantification of Human IgG and Related Fc Fusion Proteins by a Human IgG/Fc Capture ELISA
of recombinant human IgGs after production and purification for further assays. Here, we describe a human IgG/Fc capture enzyme linked immunosorbent assay (ELISA) which is simple, robust, inexpensive and specific for all types of human IgGs and related Fc fusion
consists of a cooperation between monocytes and cytophilic antibodies able to bind to the Fc receptors present on the monocyte surface. Thus human IgG1 and IgG3 are the main isotypes effective in ADCI, whereas IgG2, IgG4, and IgM are ineffective
The Human Mast Cell: An Overview
lymphocytes, and their granule contents. Mast cells can undergo activation by antigens/allergens (acting via the high-affinity receptor for immunoglobulin E, also referred to as FcεRI), superoxides, complement proteins, neuropeptides, and lipoproteins
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