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顺序：突变的人TGFβ1的胞外结构域融合在人IgG4 Fc片段的N末端。TGF-β前体蛋白区域位点33,223和225发生定点诱变，3个半胱氨酸的密码子变成丝氨酸密码子。
作用物种：人，小鼠。
特异性：结合人的TGFβ。会与小鼠的TGFβ发生反应。
生物学活性：显示TGF β1的部分生物活性，Fc结构域进行修饰，可以延长半衰期。
内毒素含量：<0.06EU/μg蛋白 (LAL测试; Lonza)。
重悬：100ul灭菌水。1×PBS稀释到需要的浓度。
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文献和实验Quantification of Human IgG and Related Fc Fusion Proteins by a Human IgG/Fc Capture ELISA
of recombinant human IgGs after production and purification for further assays. Here, we describe a human IgG/Fc capture enzyme linked immunosorbent assay (ELISA) which is simple, robust, inexpensive and specific for all types of human IgGs and related Fc fusion
Functional Analysis of Mutant Mitochondrial DNA Polymerase Proteins Involved in Human Disease
to disease. Furthermore, crucial knowledge concerning the role of pol γ in mtDNA replication and repair can be acquired. Here we present the protocols to characterize mutant DNA pol γ proteins, namely, assays for processive DNA synthesis, exonuclease activity
consists of a cooperation between monocytes and cytophilic antibodies able to bind to the Fc receptors present on the monocyte surface. Thus human IgG1 and IgG3 are the main isotypes effective in ADCI, whereas IgG2, IgG4, and IgM are ineffective
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