Recombinant Rat IL-1β

Recombinant Rat IL-1β

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  • ¥1613
  • 碧云天(beyotime)已认证
  • 2025年08月26日
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      10μg

    Species Gene ID Accession Source Length MW Tag
    Rat 24494 Q5BKB0 E. coli 153aa 17.3kDa
    About this Antibody
    Name Recombinant Rat IL-1β (Recombinant Rat Interleukin-1β; rRtIL-1β);重组大鼠白细胞介素1β
    Synonyms IL1B; IL-1F2; catabolin; Catabolin; IL-1; IL-1B; IL1-BETA; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
    Purity >96% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.1ng/ml, corresponding to a specific activity of >1.0×107IU/mg.
    Physical Appearance Sterile Filtered lyophilized (freeze-dried) liquid-like powder.
    Formulation Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 5% trehalose, 0.02% Tween-20.
    Endotoxin Less than 1EU/μg of rRtIL-1β as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background Interleukin-1beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1αand IL-1β binds to the same receptor and has similar but not identical biological properties. The mature rat IL-1β shares 90%a.a. sequence identity with cotton rat and mouse and 65% to 77% with canine, human and rhesus IL-1β.
    Amino Acid Sequence MVPIRQLHCR LRDEQQKCLV LSDPCELKAL HLNGQNISQQ VVFSMSFVQG ETSNDKIPVA LGLKGLNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKTK VEFESAQFPN WYISTSQAEH RPVFLGNSNG RDIVDFTMEP VSS

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