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- 详细信息
- 技术资料
- 规格:
10μg
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Rat | 24494 | Q5BKB0 | E. coli | 153aa | 17.3kDa | - |
| About this Antibody | |
| Name | Recombinant Rat IL-1β (Recombinant Rat Interleukin-1β; rRtIL-1β);重组大鼠白细胞介素1β |
| Synonyms | IL1B; IL-1F2; catabolin; Catabolin; IL-1; IL-1B; IL1-BETA; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta |
| Purity | >96% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.1ng/ml, corresponding to a specific activity of >1.0×107IU/mg. |
| Physical Appearance | Sterile Filtered lyophilized (freeze-dried) liquid-like powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 5% trehalose, 0.02% Tween-20. |
| Endotoxin | Less than 1EU/μg of rRtIL-1β as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Interleukin-1beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1αand IL-1β binds to the same receptor and has similar but not identical biological properties. The mature rat IL-1β shares 90%a.a. sequence identity with cotton rat and mouse and 65% to 77% with canine, human and rhesus IL-1β. |
| Amino Acid Sequence | MVPIRQLHCR LRDEQQKCLV LSDPCELKAL HLNGQNISQQ VVFSMSFVQG ETSNDKIPVA LGLKGLNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKTK VEFESAQFPN WYISTSQAEH RPVFLGNSNG RDIVDFTMEP VSS |
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Recombinant Rat IL-1β
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