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ARL13B Rabbit pAb(bs-21493R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-21493R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-21493R
    英文名称ARL13B Rabbit pAb
    中文名称ADP核糖基化因子样蛋白13b抗体
    英文别名ADP Ribosylation Factor Like GTPase 13B; ADP-Ribosylation Factor-Like 2-Like 1; ARL2-Like Protein 1; ARL2L1; ADP-Ribosylation Factor-Like Protein 2-Like 1; ADP-Ribosylation Factor-Like Protein 13B; ADP-Ribosylation Factor Like GTPase 13B; ADP-Ribosylation Factor-Like 13B; JBTS8; AR13B_HUMAN;
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ARL13B
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量49 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family

    亚基Monomer (By similarity). Interacts with PIFO. Interacts with IFT complex B components IFT46 and IFT74.
    亚细胞定位Plasma membrane
    组织特异性Expressed in the developing brain.
    翻译后修饰Sumoylation is required for PKD2 entry into cilium.
    相似性Belongs to the small GTPase superfamily. Arf family.
    功能Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidences are required to confirm these data.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Cerebrum (Rat) Lysate at 40 ug
    Cerebrum (Mouse) Lysate at 40 ug
    Primary: Anti- ARL13B (bs-21493R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49 kD
    Observed band size: 49 kD
    产品细节图片2
    Sample:
    SiHa (Human) Cell Lysate at 30 ug
    Primary: Anti-ARL13B (bs-21493R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49 kD
    Observed band size: 49 kD

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