重组人PTN北京厂家

特别提示：包括重组人PTN在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人PTN
英文名称：Recombinant Human Pleiotrophin
产品货号：GS4675
产品规格：5μg

分子量：Approximately 15.3kDa,a single non-glycosylated polypeptide chain containing 136 amino acids.
储存条件：冷冻（-20℃）

概述

Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors,whose expression is developmentally regulated.The expression pattern of these neurotrophic factors suggests function in neurogenesis,cell migration,secondary organogenetic induction,and mesoderm epithelial interaction.The expression of PTN increases during the process of brain embryogenesis and reaches maximum levels at time of birth.The physiological roles of PTN and Midkine are largely unknown,but these neurotrophins have been implicated in the pathogenesis of neuroblastomas.Recombinant human Pleiotrophin is a 15.3 kDa protein containing 136 amino acid residues and 5 intra-molecular disulfide bonds.PTN is a highly conserved protein.The amino acid sequences of human,bovine,rat,and mouse PTN share>98%identity.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity was measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons,when neurons were plated on 96 well culture plates that had been pre-coated with 100μl/well of a solution of 5-10μg/ml rHuPTN.
成分	Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4.
内毒素	Less than 0.1 EU/μg of rHuPTN as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD

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