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Frataxin Antibody / FXN

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  • ¥5832.53
  • nsjbio
  • 2026年03月31日
  • Rabbit
  • Human. Other species not known.
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant human ATRX protein was used as the immunogen for this recombinant ATRX antibody.

    • 亚型

      Rabbit IgG, kappa

    • 克隆性

      单克隆

    • 适应物种

      Human. Other species not known.

    • 宿主

      Rabbit

    • 规格

      100 ug

    产品类型:
    Primary antibody
    纯化方法:
    Purified
    通用信息:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
    产品描述:
    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [RefSeq]
    联系方式:

    生物商城:http://www.annoron.com

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    图标文献和实验
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