- ￥3031.94
- nsjbio
- V3074-20UG
- 2025年11月23日
- Mouse
- Rabies Virus of strains SAD-Vnukovo and Pitman Moore.
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified virions of SAD-Vnukovo strain followed by Pitman-Moore strain was used as the immunogen for the Rabies Virus antibody.
- 亚型：
Mouse IgG2b, kappa
- 克隆性：
单克隆
- 适应物种：
Rabies Virus of strains SAD-Vnukovo and Pitman Moore.
- 宿主：
Mouse
- 规格：
20 ug
Primary antibody
纯化方法：
Purified
通用信息：
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
产品描述：
Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This mAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
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文献和实验Lyssaviruses: Special Emphasis on Rabies Virus
Lyssavirus infection, better known as rabies, in animals or in humans, is characterized by a clinical picture of viral encephalitis. According to the WHO estimations, it is responsible for more than 50,000 human deaths each year
狂犬病病毒（rabies virus）为弹状病毒科 (rhabdoviridae)狂犬病毒属 (lyssavirus) 中血清/基因1型病毒，而2～6型称“狂犬病相关病毒”，目前仅在非洲和欧洲发现。狂犬病病毒在野生动物（狼、狐狸、鼬鼠、蝙蝠等）及家养动物（狗、猫、牛等）与人之间构成狂犬病的传播环节。人主要被病兽或带毒动物咬伤后感染。一旦受染，如不及时采取有效防治措施，可导致严重的中枢神经系统急性传染病，病死率高，在亚非拉发展中国家中每年有数万人死于狂犬病。 病毒外形呈弹状(60～
亦称恐水病（hydrophobia）病毒。人被病兽（主要是狗）咬后而受感染。有时也由狐狸传播。在南美洲及墨西哥的一部分吸血性蝙蝠也能隐性感染狂犬病病毒，通过其吸血而主要传给牛，有时也使人感染。狂犬病毒属于弹状病毒属，质粒是 75— 80× 150— 180毫微米的子弹状。感染狗时能使脑，特别是海马锥体（ Ammon’ s horn）的神经节细胞变性，在其细胞质中形成特有的包涵体尼氏（ Negre）小体。病毒存在于唾液中，由咬伤处侵入人体，通过神经纤维到达中枢神经，引起痉挛和麻痹，甚至死
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