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E7 Antibody

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  • ¥545
  • Leading Biology
  • 2025年10月30日
  • WB, IHC, E
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG1

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human

    • 库存

      100

    • 宿主

      Mouse

    • 应用范围

      WB, IHC, E

    • 规格

      100 μl

    Prouduct: We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality E7 Antibody. Functiong: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity). Summary:

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    图标文献和实验
    相关实验
    • Analysis of E7/Rb Associations

      The product of the early gene E7 is one of the major transforming proteins of human papillomaviruses (HPVs). It exerts its activity by associating with and altering the biological functions of several cellular proteins involved in the control

    • E6E7双基因共表达

      红的是E6的开放读码,兰色的是E7的开放读码,中间有几个碱基,在基因组中E6和E7就是这样排列的, 请教各位高手,我如果简单的把上述E6E7的完整片段插到真核表达系统,能否做到E6E7的共同表达?如何分析,请指教 关于双基因的表达问题:我查了一些资料,里面很有学问。

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    图标技术资料

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