- ￥5832.53
- nsjbio
- V2897SAF-100UG
- 2025年11月22日
- Mouse
- Human, Monkey, Pig, Dog, Rat and Guinea Pig. Other species not tested.
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human protein was used as the immunogen for the TLR4 antibody.
- 亚型：
Mouse IgG2a, kappa
- 克隆性：
单克隆
- 适应物种：
Human, Monkey, Pig, Dog, Rat and Guinea Pig. Other species not tested.
- 宿主：
Mouse
- 规格：
100 ug
Primary antibody
纯化方法：
Purified
通用信息：
1 mg/ml in 1X PBS; BSA free, sodium azide free
产品描述：
This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
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文献和实验Analysis of the Functional Role of Toll-Like Receptor-4 Tyrosine Phosphorylation
phosphorylation of TLR4, the principal sensor of Gram-negative bacterial lipopolysaccharide (LPS) plays a role in TLR4 signal-transducing functions. We found that LPS induced TLR4 tyrosine phosphorylation and mutations of tyrosine residues in the Toll-IL
Practical Techniques for Detection of Toll-Like Receptor-4 in the Human Intestine
to be able to respond to pathogenic organisms while at the same time maintain tolerance to normal commensal flora. Toll-like receptors (TLRs) play an important role in this delicate balance. TLRs are transmembrane noncatalytic receptor proteins that induce
人 Toll 样受体 4(TLR4) 酶联免疫分析 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，细胞上清及相关液体样本中 Toll 样受体4(TLR4) 的含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中 人 Toll 样受体4(TLR4) 水平。用纯化的人 Toll 样受体4(TLR4) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 Toll 样受体4(TLR4
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