- ￥5832.53
- nsjbio
- V2469IHC-7ML
- 2025年06月28日
- Mouse
- Human, Baboon and Monkey, Other species not tested.
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human protein was used as the immunogen for the CD35 antibody.
- 亚型：
Mouse IgG1, kappa
- 克隆性：
单克隆
- 适应物种：
Human, Baboon and Monkey, Other species not tested.
- 宿主：
Mouse
- 规格：
7 ml
Primary antibody
纯化方法：
Purified
通用信息：
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
产品描述：
Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This mAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This mAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
联系方式：
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
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文献和实验CD35 分子 CD35 常用单克隆抗体或代号： TO5,E11;(CR1) 主要表达细胞： G,M,DC,B,NKsubRBC [M] 分子质量(kDa)和结构： p250(含CCP结构域) 功 能： 结合C3b和C4b,调理吞噬,红细胞免疫粘附,调节B细胞活化 CD35 Aka CR1, C3b and C4b receptor Mediates adherence
网络 二、I型补体受体（CD35） I型补体受体（CR1、C3b/C受体，又称CD35） 为单链穿膜糖蛋白，分子量160-260kDa。CRI有四种同种异型，其分子量与基因频率分别为，A：190kDa（0.83）、B：220kDa(0.16)、C：160kDa（0.01）和D：260kDa（0.002），但它们的功能相同。CR1广泛分布
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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