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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Epidermal Melanocytes — Neonatal, Highly Pigmented
- 细胞类型:
人正常原代细胞
- 物种来源:
人源
- 器官来源:
人源
- 运输方式:
干冰或液氮
- 年限:
液氮储存10年以上
- 生长状态:
冻存
- 规格:
500,000 cells/vial
相关产品: 培养试剂 DermaLife M培养基
Lifeline® normal Human Epidermal Melanocytes – Neonatal, Secondary, Highly Pigmented (HEMn-HP), when grown in Lifeline® DermaLife M medium, provide an ideal low serum culture model, without PMA or Cholera toxin, for the accurate testing of compounds and for use in the study of cancer or dermal biology.
Lifeline® Human Epidermal Melanocytes Neonatal have been isolated, plated, and expanded in culture vessels twice before being harvested for cryopreservation to ensure the highest viability and plating efficiency.
Our HEMn-HP are quality tested in DermaLife M Medium to ensure proper growth and morphology over a period of at least 15 population doublings.
Lifeline® HEM are not exposed to antimicrobials or phenol red when cultured in Lifeline® medium, an advantage since these supplements can cause cell stress and “masking effects” that may negatively impact experimental results. Lifeline®offers these traditional supplements; however they are not needed, or recommended, to achieve optimal cell performance in most research applications.
1,000,000 cells per vial
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文献和实验. We have recently shown that multipotent dermal stem cells isolated from human neonatal foreskins are able to differentiate to multiple cell lineages, including pigmented melanocytes. The dermal stem cells grow as three-dimensional spheres in human embryonic stem
Embryonic Stem Cells as a Model for Studying Melanocyte Development
Melanocytes residing in the skin, inner ear, and uveal tract are derived from neural crest cells. They are highly dendritic, heavily pigmented, and are generally located in the epidermal basal cell layer of these areas, including hair
Cadherin-Mediated Cell-Cell Interactions
interaction of cadherins is important for the sorting of cells during morphogenesis and for maintaining the normal structure and function of tissues (5 –8 ). Cadherins are highly conserved across species and consist of three domains—i.e., an extracellular












