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Pan SUMO Antibody [APR03755G]

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  • ¥1375 - 5000
  • Leading Biology
  • APR03755G
  • 美国
  • 2025年10月03日
  • IF, IHC-P, WB
  • Rabbit
  • H, Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 靶点

      Small ubiquitin-related modifier 3, SUMO-3, SMT3 homolog 1 {ECO:0000312|HGNC:HGNC:11124}, SUMO-2, Ubiquitin-like protein SMT3A, Smt3A, SUMO3 (<a href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=11124" target="_blank">HGNC:11124</a>)

    • 浓度

      Affinity Purification

    • 应用范围

      IF, IHC-P, WB

    • 宿主

      Rabbit

    • 适应物种

      H, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 克隆性

      Polyclonal

    • 保存条件

      Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    • 形态

      Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    • 免疫原

      "This Pan SUMO antibody recognizes SUMO2 and SUMO3. This antibody is generated from rabbits immunized with a recombinant protein encoding full length human SUMO3."

    • 规格

      400 µl/200 µl/100 µl/50 µl

    规格:400 µl产品价格:¥5000.0
    规格:200 µl产品价格:¥3250.0
    规格:100 µl产品价格:¥2250.0
    规格:50 µl产品价格:¥1375.0
    分子量:11637

    细胞定位:Cytoplasm. Nucleus. Nucleus, PML body

    功能:Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 (PubMed:11451954, PubMed:18538659, PubMed:21965678). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744).

    总结:Tissue Location: Expressed predominantly in liver.

    稀释方法:IHC-P--1:100 IF--1:10~50 IHC-P--1:100~500 WB--1:1000

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