- $545
- Leading Biology
- United States
- AMM05722G
- 2025年08月19日
- WB, IHC
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human
- 库存：
100
- 宿主：
Rabbit
- 应用范围：
WB, IHC
- 靶点：
A synthetic peptide corresponding to residues in extracellular domain of human CD56/NCAM was used as an immunogen.
- 抗体名：
NCAM
- 规格：
100 μl
94574 Da
细胞定位：
Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cell membrane; Lipid-anchor, GPI- anchor Isoform 5: Secreted.
形式：
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
参考文献：
1. BA Cunningham et al., Science 236(4803) 799-806, 1987 2. AA Reyes et al., Mol Cell Biol 11(3): 1654-1661, 1991. 3. HE Beggs et al., JCB 272(13):8310-8319, 1997.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD56/NCAM antibody.
功能：
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
总结：
The neural cell adhesion molecule (NCAM/CD56) is a homophilic binding glycoprotein belonging to immunoglobulin (Ig) superfamily. It is commonly found on the surface of neurons, NK cells, glia, and neuroendocrine tissues, and it is involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM mediates axon growth, fasciculation, and cell adhesion by homophilic and heterophilic interactions (1). Due to alternative splicing, at least 27 different isoforms of NCAM mRNAs has been identified, leading to variety of NCAM isoforms (2). Three major NCAM isoforms are: 140 and 180 kDa transmembrane forms (NCAM-140, NCAM-180), and 120 kDa glycophosphatidylinositol (GPI)-linked isoform (NCAM120) (3).
联系方式：
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
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