- ￥2880
- MedChemExpress(MCE)
- 美国
- HY-106101
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C, stored under nitrogen
- 英文名：
Quinomycin A; NSC-13502
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
1 mg
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Echinomycin
CAS No. : 512-64-1
MCE 国际站：Echinomycin
产品活性：Echinomycin (Quinomycin A) 是一种有效的,细胞渗透性的低氧诱导因子-1 (HIF-1) DNA 结合活性的小分子抑制剂。Echinomycin 选择性抑制癌症干细胞，其 IC50 值为 29.4 pM。
研究领域：Metabolic Enzyme/Protease | Anti-infection
作用靶点：HIF/HIF Prolyl-Hydroxylase | Antibiotic | Bacterial
In Vitro: Echinomycin (0-10 nM; 16 hours; U251 cells) treatment significantly inhibits hypoxia-induced VEGF mRNA expression in a dose-dependent fashion. Echinomycin very potently inhibits hypoxic induction of luciferase expression in U251-HRE in a dose-dependent fashion with an EC50 of 1.2 nM.
In Vivo: Echinomycin (10 μg/kg; intravenous injection; for 40 days; NOD-SCID mice) treatment efficiently eradicates mouse lymphoma and serially transplantable human acute myeloid leukemia (AML) in xenogeneic model by preferential elimination of cancer stem cells (CSCs). HIF1α maintains mouse lymphoma CSCs by repressing a negative feedback loop in the Notch pathway.
相关产品：Rapamycin | Cycloheximide | Chloroquine | Doxorubicin hydrochloride | Bafilomycin A1 | Dexamethasone | Puromycin dihydrochloride | Dimethyl sulfoxide | Staurosporine | Actinomycin D | Deferoxamine mesylate | G-418 disulfate | Etoposide | 5-Azacytidine | Cyclosporin A | Nigericin sodium salt | Brefeldin A | Estradiol | CCCP | Ionomycin | Resveratrol | Hygromycin B | Tunicamycin | Bleomycin sulfate | Mitomycin C | Everolimus | Doxycycline hyclate | Tacrolimus | Methotrexate
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验SANDWICH ELISA FOR DETECTING SECRETE
. （a) Use at a final concentration of 2 ug/ml (1:1000 dilution). （b) Do not refreeze. Stable at 4oC for weeks. 8. Dilutions of sICAM-1 standards, 512 ng/ml -> 2 ng/ml, serial 2 fold dilutions in 1% BSA/PBS. （a) 512 ng/ml （b) 256 ng/ml （c) 128 ng
SANDWICH ELISA FOR DETECTING SECRETE
of sICAM-1 standards, 512 ng/ml -> 2 ng/ml, serial 2 fold dilutions in 1% BSA/PBS. 512 ng/ml 256 ng/ml 128 ng/ml 64 ng/ml 32 ng/ml 16 ng/ml 8 ng/ml 4 ng/ml
ELISA FOR DETECTING SECRETED ICAM-1
dilutions in 1% BSA/PBS. 512 ng/ml 256 ng/ml 128 ng/ml 64 ng/ml 32 ng/ml 16 ng/ml 8 ng/ml 4 ng/ml 2 ng/ml Procedure Diluate mAb R6.5 (or CL203) to 10
技术资料暂无技术资料 索取技术资料
