蛋白激酶A锚定蛋白7抗体

产品货号 :  jlcR11999
英文名称 :  AKAP7
中文名称 :  蛋白激酶A锚定蛋白7抗体
别    名 :  A kinase (PRKA) anchor protein 7; A kinase anchor protein 18 kD; A Kinase Anchor Protein 7; A Kinase Anchor Protein 7 Isoform Alpha; A kinase anchor protein 7 isoform beta; A kinase anchor protein 7 isoform gamma; A kinase anchor protein 7 isoforms alpha and beta; A kinase anchor protein 9 kDa; A Kinase Anchoring Protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 7 isoforms alpha and beta; AKA7A_HUMAN; AKAP 18; AKAP 7; AKAP-7 isoforms alpha and beta; AKAP15; AKAP18; Akap7; HGNC377; OTTHUMP00000040266; Protein kinase A anchoring protein 7; Protein kinase A anchoring protein 7 isoform alpha; Protein kinase A anchoring protein 7 isoform beta; Protein kinase A anchoring protein 7 isoform gamma; Protein kinase A anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms alpha/beta.  
研究领域 :  细胞生物  神经生物学  信号转导  激酶和磷酸酶  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :   Human, Mouse, Rat, Pig, Horse, Sheep,
产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  11.3kDa
细胞定位 :  细胞核 细胞浆 细胞膜
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human AKAP7:31-80/104
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍  :  A kinase (PRKA) anchor protein 7; A kinase anchor protein 18 kD; A Kinase Anchor Protein 7; A Kinase Anchor Protein 7 Isoform Alpha; A kinase anchor protein 7 isoform beta; A kinase anchor protein 7 isoform gamma; A kinase anchor protein 7 isoforms alpha and beta; A kinase anchor protein 9 kDa; A Kinase Anchoring Protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 7 isoforms alpha and beta; AKA7A_HUMAN; AKAP 18; AKAP 7; AKAP-7 isoforms alpha and beta; AKAP15; AKAP18; Akap7; HGNC377; OTTHUMP00000040266; Protein kinase A anchoring protein 7; Protein kinase A anchoring protein 7 isoform alpha; Protein kinase A anchoring protein 7 isoform beta; Protein kinase A anchoring protein 7 isoform gamma; Protein kinase A anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms alpha/beta.

Function:
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel.

Subunit:
Binds cAMP-dependent protein kinase (PKA). Interacts with PRKCA; only the cytoplasmic form is capable of interacting with PRKCA.

Subcellular Location:
Apical cell membrane. Targeted predominantly to the apical membrane and Lateral cell membrane. Targeted predominantly to the lateral membrane.

Tissue Specificity:
Expressed in brain, heart, lung, pancreas and skeletal muscle.

SWISS:
O43687

Gene ID:
9465

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片