重组大鼠IL-3β北京现货

特别提示：包括重组大鼠IL-3β在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组大鼠IL-3β
英文名称：Recombinant Rat Interleukin-3 beta
产品货号：GS4472
产品规格：5μg

分子量：Approximately 16.3kDa,a single non-glycosylated polypeptide chain containing 144 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-3(IL-3)is a type of biological signal(cytokine)which is encoded by the IL-3 gene located on chromosome 5 and produced primarily by activated T cells beside human thymic epithelial cells,activated murine mast cells,murine keratinocytes and neurons/astrocytes.It exerts its biological activities through binding to Interleukin-3 receptors included α and β subunits,but sequence analysis revealed a number of features indicative of the presence of only one β-subunit in the rat.Interleukin-3 acts in hematopoiesis by controlling the production,differentiation,and function of 2 related white cell populations of the blood,the granulocytes and the monocytes-macrophages.Furthermore,rat and human IL-3 share low homology and have not cross species activity.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine MC-9 cells is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rRtIL-3β as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MISDRGSDAH HLLRTLDCRT IALEILVKLP YPQVSGLNNS DDKANLRNST LRRVNLDEFL KSQEEFDSQD TTDIKSKLQK LKCCIPAAAS DSVLPGVYNK DLDDFKKKLR FYVIHLKDLQ PVSVSRPPQP TSSSDNFRPM TVEC

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