重组人4-1BBL价格

特别提示：包括重组人4-1BBL在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人4-1BBL
英文名称：Recombinant Human 4-1BB Ligand
产品货号：GS4541
产品规格：5μg

分子量：Approximately 19.4kDa,a single non-glycosylated polypeptide chain containing 184 amino acids.
储存条件：冷冻（-20℃）

概述

4-1BBL is a member of the tumor necrosis factor(TNF)receptor family.This receptor contributes to the clonal expansion,survival,and development of T cells.In addition,4-1BBL expression is found on dendritic cells,follicular dendritic cells,natural killer cells,granulocytes and cells of blood vessel walls at sites of inflammation.CD137 has been shown to interact with TRAF2.The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain,a 21 amino acid transmembrane domain,and a 205 amino acid extracellular domain(ECD).The human 4-1BBL ECD shares 32%and 35%a.a.identity with murine and rat ECD.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 1 EU/μg of rHu4-1BBL as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE

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