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- 2025年08月02日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
江苏省授权一级代理商
- 库存：
1
- 供应商：
无锡莱弗思生物实验器材有限公司
- CAS号：
312904-62-4
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文献和实验Oral Thrombin Inhibitor Ximelagatran
Preclinical and initial clinical experiences with the direct oral thrombin inhibitor ximelagatran demonstrated both a short and long-term potential utility for this agent in the prevention and treatment of various thromboembolic disorders
at the meeting of the International Society in Thrombosis and Haemostasis in 1993. AT is an important protease inhibitor of thrombin and factor Xa. However, AT is also able to inhibit factors IXa, XIa, XIIab, kallikrein, and plasmin. Given
Antiplatelet, Anticoagulant, and Thrombolytic Drug Interactions
, but heparin anticoagulation is unpredictable because it is an indirect thrombin inhibitor, which requires heparin cofactor II-antithrombin for its actions. Antithrombin levels vary widely in patients. In addition, the heparin-antithrombin complex is too large
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