Remibrutinib,1787294-07-8

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Remibrutinib

CAS No. : 1787294-07-8

MCE 国际站：Remibrutinib

产品活性：Remibrutinib 是一种具有口服有效活性的 bruton tyrosine kinase (BTK) 抑制剂，IC₅₀ 值为 1 nM，在血液中抑制 BTK 活性的 IC₅₀ 的值为 0.23 μM。Remibrutinib 具有研究慢性荨麻疹 (CU) 的潜力。

研究领域：Protein Tyrosine Kinase/RTK

作用靶点：Btk

In Vitro: In a biochemical enzyme assay,Remibrutinib (example 6) inhibits Btk enzymatic activity with an IC₅₀ value of 1 nM.
In vitro B cell activation assay, Remibrutinib inhibits Btk enzymatic activity in blood with an IC₅₀ value of 0.023 μM, the whole blood is collected from the abdominal aorta of anaesthetized adult male Lewis rats.

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