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GPX1 (C8C4) Rabbit mAb

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2026年01月04日
  • W
  • H
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体英文名

      GPX1 (C8C4) Rabbit mAb

    • 抗原

      synthetic peptide corresponding to the sequence of human GPX1

    • 应用范围

      W

    • 供应商

      CST

    • 保质期

      详见说明书

    • 级别

      详见MSDS文件

    • 库存

      大量

    • 适应物种

      H

    • 是否单克隆

      0

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting
    Reactivity Key:  H=Human
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Isotype
    W H Endogenous 22 Rabbit IgG
    Protocols
    Specificity / Sensitivity

    GPX1 (C8C4) Rabbit mAb detects endogenous levels of total GPX1 protein.

    Source / Purification

    GPX1 (C8C4) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to the sequence of human GPX1.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from 293 and THP-1 cells using GPX1 (C8C4) Rabbit mAb.

    Background

    Glutathione peroxidase 1 (GPX1) is a cytosolic selenoprotein which reduces hydrogen peroxide to water (1). GPX1 is the most abundant and ubiquitous among the five GPX isoforms identified so far (2). It is an important component in the anti-oxidative defense in cells and is associated with a variety of disease conditions, such as colon cancer (3), coronary artery disease (4) and insulin resistance (1).

    1. McClung, J.P. et al. (2004) Proc. Natl. Acad. Sci. USA 101, 8852-8857.
    2. Hamanishi, T. et al. (2004) Diabetes 53, 2455-2460.
    3. Drew, J.E. et al. (2005) FEBS Lett. 579, 6135-6139.
    4. Winter, J.P. et al. (2003) Coron. Artery Dis. 14, 149-153.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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    图标文献和实验
    相关实验
    • Rabbit Whole Embryo Culture

      Although the rabbit is used extensively in developmental toxicity testing, relatively little is known about the fundamental developmental biology of this species let alone mechanisms underlying developmental toxicity. This paucity

    • Purification of mAb (IgG)

        Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers

    • Testing Rabbit Bleeds By Elisa

      as a solid if soluble. Mix, adding glutaraldehyde last. Peptide and BSA turn a little yellow even before adding glutaraldehyde. Incubate 90'' at 37 deg C. Add 0.1 volumes of 0.1 M NaBH4 in 0.1 M NaHCO3. There will be some bubbling. Add

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