- 询价
- Cell Signaling Technology
- 3794
- USA
- 2025年12月26日
- W
- Rabbit
- H,M,R,Mk
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
SKAR α/β Antibody
- 抗原：
synthetic peptide corresponding to amino terminal residues of human SKAR
- 应用范围：
W
- 宿主：
Rabbit
- 库存：
大量
- 适应物种：
H,M,R,Mk
- 级别：
详见MSDS文件
- 保质期：
详见说明书
- 供应商：
CST
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse R=Rat Mk=Monkey
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H M R Mk | Endogenous | 46, 43 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | SKARα/β Antibody detects endogenous levels of total SKAR protein. The antibody recognizes both the α and the β isoforms. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino terminal residues of human SKAR. Antibodies are purified using protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from various cell types using SKARα/β Antibody. |
| Background | p70 S6 kinase is a mitogen activated Ser/Thr protein kinase downstream of phosphoinositide-3 kinase (PI3K) and the target of rapamycin, FRAP/mTOR. p70 S6 kinase is required for cell growth and cell cycle progression (1,2). SKAR is a recently discovered substrate of S6K1. SKAR exists in two isoforms, α and β, the latter having a 29 amino acid truncation. Phosphorylation of SKAR is mitogen-induced and sensitive to rapamycin. Reduction in SKAR protein levels results in decreased cell size, further implicating SKAR in cell growth control (3). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验祝贺〖雅裕睿安〗成为Signalway Antibody(SAB)独家
、 Wnt 通道 /β- 连环素等领域提供最优质的产品。 Signalway Antibody(SAB)( 美国)多年来一直致力于磷酸化蛋白抗体的研发，生产和销售。公司拥有抗磷酸化蛋白抗体库产业化大规模技术平台，处于国内领先，国际先进水平。公司建立了一整套完善的生产、质量控制、产品保存、运输及销售的管理体系。 公司现已在美洲、欧洲和亚洲成立了销售中心，产品销往美国、英国、德国、日本等40多个国家，受到广泛好评。
制备蛋白提取物1. Prepare extracts from cultured cells or tissues with our Trident Extraction Kits.The total number of cells per ml and the cell equivalent loaded per lane of gel should be optimized specifically for each protein and antibody.2. Determine
【资源】全面归类网址：毕赤酵母表达各种来源蛋白（细菌，真菌，植物，人类等）
giganteus a-sarcin ribotoxinS, 1 mg/L, synthetic native,PHO1[77]Aspergillus niger β-glucosidaseS, 0.5 g/L, PHO1313Aspergillus niger phytase (phyA)S, 65 U/ml, α-MF[78]Aspergillus niger endo-β-1,4-xylanaseS, 60 mg/L, SUC2, native311Barley glucosidase345Candida
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