DHX29 (D19E10) Rabbit mAb

DHX29 (D19E10) Rabbit mAb

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年12月03日
  • W, IP
  • H,M,Mk
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    • 详细信息
    • 技术资料
    • 抗体英文名

      DHX29 (D19E10) Rabbit mAb

    • 抗原

      synthetic peptide corresponding to residues near the carboxy terminus of human DHX29 protein

    • 应用范围

      W, IP

    • 适应物种

      H,M,Mk

    • 保质期

      详见说明书

    • 库存

      大量

    • 级别

      详见MSDS文件

    • 供应商

      CST

    • 是否单克隆

      1

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IP=Immunoprecipitation
    Reactivity Key:  H=Human  M=Mouse  Mk=Monkey
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Isotype
    W IP H M Mk Endogenous 155 Rabbit IgG
    Protocols
    Specificity / Sensitivity

    DHX29 (D19E10) Rabbit mAb recognizes endogenous levels of total DHX29 protein.

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human DHX29 protein.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from HT-29 and HeLa cells using DHX29 (D19E10) Rabbit mAb.

    Background

    DHX29 is an ATP-dependent RNA helicase that belongs to the DEAD-box helicase family (DEAH subfamily). DHX29 contains one central helicase and one helicase at the carboxy-terminal domain (1). Its function has not been fully established but DHX29 was recently shown to facilitate translation initiation on mRNAs with structured 5' untranslated regions (2). DHX29 binds 40S subunits and hydrolyzes ATP, GTP, UTP, and CTP. Hydrolysis of nucleotide triphosphates by DHX29 is strongly stimulated by 43S complexes and is required for DHX29 activity in promoting 48S complex formation (2).

    1. de la Cruz, J. et al. (1999) Trends Biochem Sci 24, 192-8.
    2. Pisareva, V.P. et al. (2008) Cell 135, 1237-50.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !


    For Research Use Only. Not For Use In Diagnostic Procedures.

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