MDH2 Antibody

MDH2 Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年11月14日
  • W
  • Rabbit
  • H,M,R
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    • 详细信息
    • 技术资料
    • 抗体英文名

      MDH2 Antibody

    • 抗原

      synthetic peptide corresponding to residues near the carboxy terminus of human MDH2 protein

    • 应用范围

      W

    • 宿主

      Rabbit

    • 保质期

      详见说明书

    • 级别

      详见MSDS文件

    • 库存

      大量

    • 适应物种

      H,M,R

    • 供应商

      CST

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting
    Reactivity Key:  H=Human  M=Mouse  R=Rat
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W H M R Endogenous 35 Rabbit
    Protocols
    Specificity / Sensitivity

    MDH2 Antibody recognizes endogenous levels of total MDH2 protein.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MDH2 protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from various cell lines using MDH2 Antibody.

    Background

    Malate dehydrogenase (MDH) is a key enzyme in the tricarboxylic acid cycle and malate/aspartate shuttle (1,2). MDH is widely expressed in organisms from most bacteria to all eukaryotes (2). The cytoplasmic MDH isoenzyme (cMDH or MDH1) primarily reduces oxaloacetate to malate in the malate/aspartate shuttle (1,2,3). The major function of mitochondrial MDH isoenzyme (mMDH or MDH2) is to oxidize malate to oxaloacetate in the tricarboxylic acid cycle (1,2).

    1. Matsuda, T. et al. (2010) J Pharmacol Sci 112, 320-6.
    2. Minárik, P. et al. (2002) Gen Physiol Biophys 21, 257-65.
    3. Joh, T. et al. (1987) J Biol Chem 262, 15127-31.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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