- 询价
- Cell Signaling Technology
- 2663
- USA
- 2025年10月18日
- W, IP
- Rabbit
- M,H,R
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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名：
Deltex-2 Antibody
- 抗原：
synthetic peptide corresponding to residues surrounding Ala607 of human Deltex-2
- 应用范围：
W, IP
- 宿主：
Rabbit
- 适应物种：
M,H,R
- 库存：
大量
- 级别：
详见MSDS文件
- 供应商：
CST
- 保质期：
详见说明书
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP | M (H) (R) | Transfected Only | 70 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Deltex-2 Antibody detects transfected levels of total Deltex-2 protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala607 of human Deltex-2. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from COS cells, untransfected or transfected with mouse Deltex-2, using Deltex-2 Antibody. |
| Background | Deltex (DTX) encodes a putative E3 ubiquitin ligase first identified from Drosophila and shown to modulate Notch signaling (1). Several mammalian Deltex homologs have been isolated (2,3), all containing a pair of WWE repeats, a proline-rich region, and a Ring-finger domain (4,5). Deltex binds to the ankyrin-repeat domain of Notch and is capable of regulating Notch signaling positively or negatively in different systems (4,6). In addition, Deltex can also form homo-multimers (4). While Deltex has been implicated in Notch signaling regulation of lymphocyte development, this signal modifier may also have a transcriptional function independent of Notch (3, 6-8).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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