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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated peptide encompassing a sequence within the C-term region of rat ribosomal S6 kinase 2.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
B, D, Ck, M, R, H
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated peptide encompassing a sequence within the C-term region of rat ribosomal S6 kinase 2.
- 目录编号:
253212
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
Ribosomal S6 kinase 2
- 抗体英文名:
Ribosomal S6 kinase 2 Antibody
- 抗体名:
Ribosomal S6 kinase 2 Antibody
- 规格:
0.1 ml
Ribosomal S6 kinase 2 Antibody产品详细介绍:
| 产品名称: | Ribosomal S6 kinase 2 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253212 |
| 规格: | 0.1 ml |
| 产品描述: | The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated peptide encompassing a sequence within the C-term region of rat ribosomal S6 kinase 2. |
| 适用物种: | B, D, Ck, M, R, H |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:1,000 |
| 别名: | Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Protein-tyrosine kinase Mpk-9; Ribosomal S6 kinase 3; RSK-3; pp90RSK3; Rps6ka2; Mapkapk1c; Rsk3 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验ERK-MAP Kinase Signaling in the Cytoplasm
. We describe two complementary methods for quantitatively measuring ERK activity toward the cytoplasmic p90 ribosomal S6 kinase (RSK). The first method is a straightforward immunoblot of endogenous ERK and RSK phosphoepitopes using phospho-specific antibodies. Infrared
构成核糖体的蛋白质。大肠杆菌核糖体蛋白的初级结构均被确定。大肠杆菌核糖体的 30S亚基含 S1 — S21 共 21种蛋白质, 50S亚基含 L1— L34共 34种蛋白质。这些蛋白质已被全部分离纯化。分子量约 1万到 3万。除 S6 、 L7 、 L12 之外全是碱性蛋白质。这些蛋白质是免疫学上独立的蛋白质,只有 L7 、 L1 2 显示出相互交叉反应。已知 L7 与 L1 2 是同一蛋白质, L7 的 N末端被乙酰化。已经确定了几种蛋白的一级结构。机能已经
The Extracellular Signal-Regulated Kinase (ERK) Cascade in Neuronal Cell Signaling
of both the ribosomal protein S6 and of the histone H3 is completely prevented by a chemical inhibition of the ERK pathway, this ex-vivo system can be exploited in the future to investigate the regulation of the ERK cascade using slices from LV-injected
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