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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of PGR(aa731-909) expressed in E. coli. <br>
- 亚型:
Mouse IgG2b
- 形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件:
Store at -20°C
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 保质期:
1-2年
- 抗原来源:
Purified recombinant fragment of PGR(aa731-909) expressed in E. coli. <br>
- 目录编号:
252770
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
WB
- 浓度:
见详细说明信息
- 靶点:
PGR (2C11)
- 抗体英文名:
PGR (2C11) Antibody
- 抗体名:
PGR (2C11) Antibody
- 规格:
0.1 ml
PGR (2C11) Antibody产品详细介绍:
| 产品名称: | PGR (2C11) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252770 |
| 规格: | 0.1 ml |
| 产品描述: | PR (Progesterone receptor) is a transcription factor that is regulated by the binding of their cognate ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG2b |
| 免疫原: | Purified recombinant fragment of PGR(aa731-909) expressed in E. coli. |
| 适用物种: | H |
| 应用范围: | WB |
| 应用说明: | WB: 1:500-1:2000; |
| 别名: | Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3; PGR; NR3C3 |
| 形态: | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件: | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
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文献和实验双特异抗体(Bispecific antibody)的简介和制作方法
、双特异抗体简介双特异抗体(Bispecific antibody)是含有两个不同配体结合位点的免疫球蛋白分子。自然状态下不存在双特异性抗体,只能通过特殊方法进行制备。以往双特异抗体的制备方法有化学交联法,杂合F(ab')2 分子法和鼠杂交瘤法等。化学交联法生产双特异抗体的异源性,批与批之间的不稳定性,以及抗体特异性易受某些修饰或不当连接而改变的特性,使得该法生产的双特异抗体不适于体内使用。以巯基交联蛋白酶消化片断F(ab')生产的双特异杂交分子,成分虽较均一,但费时费力,且产量很低。杂交瘤法生产
concentration used, titration of the activating reagents and the optimal culture period for the best activation response. Protocol A: Stimulation of mouse peripheral T cells with plate-bound 145-2C11 monoclonal antibody; MTT assay for detection of cellular
T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
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