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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of EphB1(aa19-133) expressed in E. coli. <br>
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件:
Store at -20°C
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 保质期:
1-2年
- 抗原来源:
Purified recombinant fragment of EphB1(aa19-133) expressed in E. coli. <br>
- 目录编号:
252754
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
WB, IHC
- 浓度:
见详细说明信息
- 靶点:
EhpB1 (5F10)
- 抗体英文名:
EhpB1 (5F10) Antibody
- 抗体名:
EhpB1 (5F10) Antibody
- 规格:
0.1 ml
EhpB1 (5F10) Antibody产品详细介绍:
| 产品名称: | EhpB1 (5F10) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252754 |
| 规格: | 0.1 ml |
| 产品描述: | EhpB1 (EPH receptor B1) is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Purified recombinant fragment of EphB1(aa19-133) expressed in E. coli. |
| 适用物种: | H |
| 应用范围: | WB, IHC |
| 应用说明: | WB: 1:500-1:2000; IHC: 1:200-1:1000; |
| 别名: | Ephrin type-B receptor 1; ELK; EPH tyrosine kinase 2; EPH-like kinase 6; EK6; hEK6; Neuronally-expressed EPH-related tyrosine kinase; Tyrosine-protein kinase receptor; EPH-2; ELK; EPHT2; HEK6; NET; EPHT2; EPHB1 |
| 形态: | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件: | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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免疫,并抑制了 LLC 荷瘤小鼠的骨髓生成(图 4 D-G)。因此,这些结果表明,拮抗 MC5R 可以增强抗肿瘤免疫功能,具有潜在的抗肿瘤作用,即使在抗 PD-1 耐药的肿瘤中也是如此。 髓系细胞在限制 ICT 的疗效中起主要作用。因此作者进一步研究了抑制 MC5R 依赖的骨髓生成是否提高了 ICT 的效率或克服了 ICT 的耐药性。结果发现,在 MCA205、LLC 或 B16F10-GMCSF 荷瘤小鼠中,联合使用抗 PD-1 抗体和 MC5R 特异性拮抗剂对肿瘤的抑制作用要比二者单独使用要强得多(图
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