- ￥3000 - 3999
- Abbiotec
- 美国
- 252752
- 2025年12月09日
- WB, IHC
- Mouse
- H
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- 详细信息
- 技术资料
- 免疫原：
Purified recombinant fragment of CRYAB(aa1-175) expressed in E. coli.
- 亚型：
Mouse IgG2a
- 形态：
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件：
Store at -20°C
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 抗原来源：
Purified recombinant fragment of CRYAB(aa1-175) expressed in E. coli.
- 目录编号：
252752
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
WB, IHC
- 浓度：
见详细说明信息
- 靶点：
CRYAB (1D11)
- 抗体英文名：
CRYAB (1D11) Antibody
- 抗体名：
CRYAB (1D11) Antibody
- 规格：
0.1 ml
CRYAB (1D11) Antibody产品详细介绍：
| 产品名称： | CRYAB (1D11) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252752 |
| 规格： | 0.1 ml |
| 产品描述： | CRYAB (Alpha B crystallin) is a molecular chaperone. Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG2a |
| 免疫原： | Purified recombinant fragment of CRYAB(aa1-175) expressed in E. coli. |
| 适用物种： | H |
| 应用范围： | WB, IHC |
| 应用说明： | WB: 1:500-1:2000; IHC: 1:200-1:1000; |
| 别名： | Alpha-crystallin B chain; Alpha(B)-crystallin; Heat shock protein beta-5; HspB5; Renal carcinoma antigen NY-REN-27; Rosenthal fiber component; CRYA2; CTPP2; HSPB5; CRYAB |
| 形态： | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件： | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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CRYAB (1D11) Antibody_CRYAB (1D11)抗体
￥3000 - 3999
