PROZ (2B4) Antibody_PROZ (2B4)抗体

PROZ (2B4) Antibody_PROZ (2B4)

抗体
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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 252902
  • 2025年07月13日
  • WB
  • Mouse
  • H
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    • 详细信息
    • 技术资料
    • 免疫原

      Purified recombinant fragment of PROZ expressed in E. coli.

    • 亚型

      Mouse IgG1

    • 形态

      Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

    • 保存条件

      Store at -20°C

    • 克隆性

      单克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H

    • 保质期

      1-2年

    • 抗原来源

      Purified recombinant fragment of PROZ expressed in E. coli.

    • 目录编号

      252902

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      Abbiotec

    • 宿主

      Mouse

    • 应用范围

      WB

    • 浓度

      见详细说明信息

    • 靶点

      PROZ (2B4)

    • 抗体英文名

      PROZ (2B4) Antibody

    • 抗体名

      PROZ (2B4) Antibody

    • 规格

      0.1 ml

    PROZ (2B4) Antibody_PROZ (2B4)
    PROZ (2B4) Antibody产品详细介绍:
    产品名称: PROZ (2B4) Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 252902
    规格: 0.1 ml
    产品描述: PROZ (Protein Z) is a 396 amino acids long (~62 kDa) vitamin K-dependent plasma glycoprotein. It has four domains: a gla-rich region, two EGF-like domains and a trypsin-like domain. It lacks the serine residue that would make it catalytically active as a serine protease. It is a member of the coagulation cascade, the group of blood proteins that leads to the formation of blood clots. It is vitamin K-dependent, and its functionality is therefore impaired in warfarin therapy. It is a glycoprotein. Although it is not enzymatically active, it is structurally related to several serine proteases of the coagulation cascade: factors VII, IX, X and protein C. The carboxyglutamate residues (which require vitamin K) bind protein Z to phospholipid surfaces. The main role of protein Z appears to be the degradation of factor Xa. This is done by protein Z-related protease inhibitor (ZPI), but the reaction is accelerated 1000-fold by the presence of protein Z. ZPI also degrades factor XI, but this reaction does not require the presence of protein Z. ZPI deficiency states have been associated with a propensity to thrombosis.
    克隆类型: Mouse Monoclonal Antibody
    亚型: Mouse IgG1
    免疫原: Purified recombinant fragment of PROZ expressed in E. coli.
    适用物种: H
    应用范围: WB
    应用说明: WB: 1:500-1:2000;
    别名: Vitamin K-dependent protein Z; PROZ
    形态: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
    保存条件: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    PROZ (2B4) Antibody_PROZ (2B4) PROZ (2B4) Antibody_PROZ (2B4)

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