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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of MYL3 expressed in E. coli.
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件:
Store at -20°C
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, R
- 保质期:
1-2年
- 抗原来源:
Purified recombinant fragment of MYL3 expressed in E. coli.
- 目录编号:
252882
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
MYL3 (3F8)
- 抗体英文名:
MYL3 (3F8) Antibody
- 抗体名:
MYL3 (3F8) Antibody
- 规格:
0.1 ml
MYL3 (3F8) Antibody产品详细介绍:
| 产品名称: | MYL3 (3F8) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252882 |
| 规格: | 0.1 ml |
| 产品描述: | MYL3 (Myosin light chain 3, an alkali light chain) is referred as both the ventricular isoform and the slow skeletal muscle isoform. Myosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Purified recombinant fragment of MYL3 expressed in E. coli. |
| 适用物种: | H, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 10000; WB: 1:500-1:2000; IHC: 1:200-1:1000 |
| 别名: | Myosin light chain 3; Cardiac myosin light chain 1; CMLC1; Myosin light chain 1, slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain; MYL3 |
| 形态: | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件: | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验相关实验
通过免疫组化的方法分析侵袭性乳腺癌中 GD2 表达的临床和病理相关性
来自纽约癌症中心的学者,对 396 例乳腺癌组织免疫组化染色 GD2 靶点,其结果与临床病理特征、生存结果进行相关性分析,结果支持 GD2 可以作为潜在治疗靶点。 双唾液酸神经节苷脂 GD2 是一种细胞表面相关抗原,在神经外胚层来源的肿瘤上表达,可作为某些癌症类型的免疫治疗靶点。但目前关于乳腺癌和 GD2 表达相关性的研究资料较少,来自纽约癌症中心的学者们研究了 GD2 作为潜在靶向治疗中生物标志物的可能性。研究团队收集了 396 例不同组织学类型的乳腺癌组织,用抗 GD2 3F8 单克隆抗体
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MYL3 (3F8) Antibody_MYL3 (3F8)抗体
¥3000 - 3999









