- ￥3000 - 3999
- Abbiotec
- 美国
- 252542
- 2025年11月20日
- E, WB
- Rabbit
- R, B, D, Ck, X, Zf
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser327 of rat GABAA receptor, g2.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
R, B, D, Ck, X, Zf
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser327 of rat GABAA receptor, g2.
- 目录编号：
252542
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
GABAA Receptor gamma-2 (Ser327)
- 抗体英文名：
GABAA Receptor gamma-2 (Ser327) Antibody
- 抗体名：
GABAA Receptor gamma-2 (Ser327) Antibody
- 规格：
0.1 ml
GABAA Receptor gamma-2 (Ser327) Antibody产品详细介绍：
| 产品名称： | GABAA Receptor gamma-2 (Ser327) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252542 |
| 规格： | 0.1 ml |
| 产品描述： | Gamma-aminobutyric acid receptor subunit gamma-2 (GABAA Receptor, g2) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. It has recently been suggested that PKC regulates the sensitivity of GABAA a1b2g2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of g2. |
| 克隆类型： | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser327 of rat GABAA receptor, g2. |
| 适用物种： | R, B, D, Ck, X, Zf |
| 应用范围： | E, WB |
| 应用说明： | E: 1:1,000; WB: 1:1,000 |
| 别名： | Gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor subunit gamma-2; Gabrg2; GABAA Receptor, g2 |
| 形态： | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Benzodiazepine Binding to GABAA Receptors
of) GABAA receptor subtypes can be identified. Preparation of membrane suspensions for this procedure is described in a Support Protocol, and five Alternate Protocols are provided for the identification of diazepam?sensitive GABAA receptors, the ?1?subtype
), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade
Coating of Platelets with Antibody in vitro
gamma receptor (FcgammaR) reactive reagents. Eur J Haematol 70(2): 67-74.
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