- ￥3000 - 3999
- Abbiotec
- 美国
- 252541
- 2025年11月20日
- E, WB
- Rabbit
- B, D, Ck, H, M, X, Zf
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser408/409 of rat GAGAA receptor, b3.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
B, D, Ck, H, M, X, Zf
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser408/409 of rat GAGAA receptor, b3.
- 目录编号：
252541
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
GABAA Receptor beta-3 (Ser408/409)
- 抗体英文名：
GABAA Receptor beta-3 (Ser408/409) Antibody
- 抗体名：
GABAA Receptor beta-3 (Ser408/409) Antibody
- 规格：
0.1 ml
GABAA Receptor beta-3 (Ser408/409) Antibody产品详细介绍：
| 产品名称： | GABAA Receptor beta-3 (Ser408/409) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252541 |
| 规格： | 0.1 ml |
| 产品描述： | Gamma-aminobutyric acid receptor subunit beta-3 (GABAA Receptor, b3) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Phosphorylation of serine 408 and serine 409 within the beta-3 subunit have been shown to be critical for the functional modulation of beta-3 containing recombinant receptors. |
| 克隆类型： | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser408/409 of rat GAGAA receptor, b3. |
| 适用物种： | B, D, Ck, H, M, X, Zf |
| 应用范围： | E, WB |
| 应用说明： | E: 1:1,000; WB: 1:1,000 |
| 别名： | Gamma-aminobutyric acid receptor subunit beta-3; GABA(A) receptor subunit beta-3; Gabrb3; Gabrb-3 |
| 形态： | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Synaptoneurosomes: A Preparation for Studying Subhippocampal GABAA Receptor Activity
by postsynaptic mechanisms. In the past, isolated membrane fractions enriched in postsynaptic densities have been used for this purpose (1 ). However, this fraction of postsynaptic densities is not appropriate to study receptor-mediated signal transduction
下调不能说明活性降低，因为决定GSK3-beta的活性的还与其磷酸化的比例和磷酸化的位点有关。所以你除了要做GSK3-beta总的蛋白表达之外，还要做磷酸化的GSK3-beta的蛋白表达。 （2）应该活性形式和非活性形式都做。一般来讲，GSK3-beta在Ser9位点磷酸化之后活性收到抑制，而在216位点磷酸化之后，其活性收到加强。因此建议将GSK3-beta的两个磷酸化位点都做了，另外还要同时检测GSK3-beta的总蛋白表达，这样才能全面的说明问题。
GABAA Receptor 1 Subunit (Gabra1) Knockout Mice: Review and New Results
The inhibitory GABAA receptor plays important roles in the control of anxiety and sleep behavior. The α1 subunit-containing GABAA receptor is the major subtype, contributing to about 60% of all GABAA receptors in the brain. In this chapter
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