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- MedChemExpress(MCE)
- 美国
- HY-12885C
- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C, sealed storage, away from moisture and light
- 英文名：
ADU-S100 enantiomer ammonium salt; MIW815 enantiomer ammonium salt; ML RR-S2 CDA enantiomer ammonium salt
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL///1 mg
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ADU-S100 enantiomer ammonium salt
MCE 国际站：ADU-S100 enantiomer ammonium salt
产品活性：ADU-S100 enantiomer ammonium salt (MIW815 enantiomer ammonium salt) 是 ADU-S100 的低活性对映异构体。ADU-S100 是干扰素基因刺激物的激活剂 (STING)。
研究领域：Others
作用靶点：Others
In Vitro: STING is a transmembrane protein localized to the endoplasmic reticulum that undergoes a conformational change in response to direct binding of cyclic dinucleotides, resulting in a downstream signaling cascade involving TBK1 activation, IRF-3 phosphorylation, and production of IFN-β and other cytokines. The direct activation of the STING pathway might be an effective therapeutic strategy to promote broad tumor-initiated T cell priming against tumor antigen repertoire.
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文献和实验Modification of the 5′ Terminus of Oligodeoxyribonucleotides for Conjugation with Ligands
or 6‐aminocaproic acid, 1,8‐diazabicyclo[5.4.0]undec‐7‐ene (DBU) salt (Aldrich), in pyridine 12 mg/mL 1,5‐diaminopentane
. (a ) Synthesized 5′‐dTTP after NaCl‐ethanol precipitation and RP‐HPLC purification (retention time: 19.8 min); (b ) 5′‐dTTP standard (retention time: 19.4 min); (c ) co‐injection of a and b (retention time: 19.4 min).
Measurement of Oxygen Radicals and Lipid Peroxidation in Neural Tissues
) Salicylate (Aldrich) Tissue samples of interest: ∼500‐mg pieces, dissected and immediately frozen in liquid nitrogen, and stored at –80°C
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