- ￥2260
- LSM Bio
- 进口
- PAab09950
- 2025年07月17日
- ELISA, WB, IHC
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
vascular cell adhesion molecule 1
- 亚型：
IgG1
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
monoclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Mouse
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB, IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
vascular cell adhesion molecule 1
- 抗体英文名：
VCAM-1 antibody
- 抗体名：
VCAM-1 antibody
- 规格：
100μl
VCAM-1 antibody
Product Name VCAM-1 antibody
Catalog No PAab09950
Packing 100ul
Form liquid
Alternative Name CD106, DKFZp779G2333, INCAM 100, L1CAM, V CAM 1, VCAM 1, VCAM1
Purification protein A+G purified
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Immunogen vascular cell adhesion molecule 1
Specificity Human, Mouse
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:500 - 1:1000; IHC: 1:50 - 1:500
IHC use Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using PAab09950 (VCAM-1 antibody) at dilution of 1:400
WB use
human spleen tissue were subjected to SDS PAGE followed by western blot with PAab09950( VCAM-1 Antibody) at dilution of 1:800
Protein Information
Gene ID
Uniprot ID P19320
Calculated MW 105 kDa
Research Area Signal Transduction, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
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文献和实验Cell adhesion molecules (CAMs) such as intercellular adhesion molecule (ICAM-1), vascular adhesion molecule (VCAM-1), and lymphocyte function-associated antigen (LFA-1) facilitate interaction among cells of various lineages
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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