- ￥2260
- LSM Bio
- 进口
- PAab09843
- 2025年07月11日
- ELISA, WB
- E. coli - derived recombinant protein
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
glutamate decarboxylase 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
glutamate decarboxylase 1
- 抗体英文名：
GAD1 antibody
- 抗体名：
GAD1 antibody
- 规格：
100μl
GAD1 antibody
Product Name GAD1 antibody
Catalog No PAab09843
Packing 100ul
Form liquid
Alternative Name FLJ45882, GAD, GAD 67, GAD1, GAD67, Glutamate decarboxylase 1, SCP
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Immunogen glutamate decarboxylase 1
Specificity Human, Mouse, Rat
Tested Application ELISA, WB
Recommended dilution WB: 1:500 - 1:2000
IHC use
WB use
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09843( GAD1 Antibody) at dilution of 1:1000
Protein Information
Gene ID 2571
Uniprot ID Q99259
Calculated MW 348 kDa
Research Area Neuroscience, Stem Cells, Metabolism
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