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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
myeloid differentiation primary response gene
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
myeloid differentiation primary response gene
- 抗体英文名:
MYD88 antibody
- 抗体名:
MYD88 antibody
- 规格:
100μl
MYD88 antibody
Product Name MYD88 antibody
Catalog No PAab09835
Packing 100ul
Form liquid
Alternative Name MYD88, MYD88D
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Immunogen myeloid differentiation primary response gene
Specificity Human, Mouse, Rat
Tested Application ELISA, WB
Recommended dilution WB: 1:500 - 1:2000
IHC use
WB use
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09835(MYD88 antibody) at dilution of 1:1000
Protein Information
Gene ID 4615
Uniprot ID Q99836
Calculated MW 90 kDa
Research Area Immunology, Signal Transduction
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
zhang7513 请问各位大侠! Myd88代表什么意思?请指教!谢谢! 77472087 髓样分化蛋白-88 myeloid differentiation factor 88, MyD88 happylife004007 髓样分化蛋白88, 它是一种接头蛋白分子,含有TIR结构域,在天然免疫中介导信号传导。 zhouasd 细胞分化因子88
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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