- ￥2260
- LSM Bio
- 进口
- PAab10077
- 2025年07月10日
- ELISA, IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD14 molecule
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
CD14 molecule
- 抗体英文名：
CD14 antibody
- 抗体名：
CD14 antibody
- 规格：
100μl
CD14 antibody
Product Name CD14 antibody
Catalog No PAab10077
Packing 100ul
Form liquid
Alternative Name CD14, CD14 molecule
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).
Immunogen CD14 molecule
Specificity Human
Tested Application ELISA, IHC
Recommended dilution IHC: 1:20-1:200
IHC use Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab10077(CD14 Antibody) at dilution of 1:200
WB use
Protein Information
Gene ID 929
Uniprot ID P08571
Calculated MW 50-55 kDa
Research Area Stem Cells, Immunology, Signal Transduction, Cancer
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文献和实验CD14 分子 CD14 常用单克隆抗体或代号：Mo2,UCHM1,LeuM3,MY4 主要表达细胞：M,G,DC,LHC [M] 分子质量(kDa)和结构：gp55(GPI连接) 功 能：LPS/LBP复合体受体 CD14 Aka lipopolysaccharide (LPS) receptor, endotoxin receptor Binding
Dendritic Cell Generation from Highly Purified CD14+Monocytes
Dendritic cells (DC) play a pivotal role in the function of the immune system, for they are the primary antigen-presenting cells (APC) in the activation of naive T-lymphocyte responses (1 ). Recent studies have uncovered complexity in the DC
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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