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20 µg/100 µg
| 规格: | 20 µg | 产品价格: | ¥1980 |
|---|---|---|---|
| 规格: | 100 µg | 产品价格: | ¥4680 |
蛋白名称:CD22蛋白, CD22 protein
蛋白构建:A DNA sequence encoding the human CD22 (P20273-1) (Met1-Arg687) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE.
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg protein as determined by the LAL method.
预测N端:Asp 20
蛋白分子量:The recombinant human CD22 consists of 679 amino acids and predicts a molecular mass of 76.6 kDa.
蛋白NP号:P20273-1
蛋白氨基酸序列:Met1-Arg687
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验CD22 分子 CD22 常用单克隆抗体或代号: B3,HD39,Leu14,SHCL- 1,HC2 (BL- CAM) 主要表达细胞: B [B] 分子质量(kDa)和结构: gp130/140,髓鞘(磷)脂相关蛋白类似物(MAG)(IgSF) 功 能: 与CD45RO、CD75结合,B细胞粘附到M、红细胞,介导B- B、B- T细胞相互作用 CD22 Aka B
Anti-CD22 Onconase: Preparation and Characterization
Antibodies can be conjugated to effector molecules to derive targeted therapeutics with properties such as cell-specific cytotoxicity. The murine anti-CD22 antibody RFB4 linked to a member of the ribonuclease A superfamily, Onconase (Onc
,但浆细胞不表达CD22。 CD22胞质区有6个酪氨酸残基,其中3个组成ITlM(1xYXXL基序),可结合带有SH2结构域的蛋白酪氨酸磷酸酶如SHP-1,因而CD22是B细胞活化中的抑制性受体。
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