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- 2026年06月02日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C, sealed storage, away from moisture
- 英文名：
IdB 1027
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
528-58-5
- 规格：
1 mg/5 mg/10 mg/20 mg
| 规格： | 1 mg | 产品价格： | ￥525.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1380.0 |
| 规格： | 10 mg | 产品价格： | ￥2350.0 |
| 规格： | 20 mg | 产品价格： | ￥4000.0 |
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Cyanidin Chloride
CAS No. : 528-58-5
MCE 国际站：Cyanidin Chloride
产品活性：Cyanidin Chloride (IdB 1027) 是花青素的一个亚类，具有抗氧化和抗癌作用。Cyanidin Chloride (IdB 1027) 抑制破骨细胞形成，羟基磷灰石吸收和 NF-κB 配体 (RANKL) 诱导的破骨细胞标记基因表达的受体激活。
研究领域：NF-κB
作用靶点：RANKL/RANK
In Vitro: Cyanidin Chloride (IdB 1027) inhibits receptor activator of NF-κB ligand (RANKL)-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK). Cyanidin Chloride (IdB 1027) abrogates RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos.
In Vivo: Cyanidin Chloride (IdB 1027) protects against OVX-induced bone loss in OVX-induced osteoporosis mouse model.
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文献和实验Abstract Previous studies by Stachel and colleagues indicate that lithium chloride induction of post-midblastular Brachydanio rerio embryos results in deficiencies in normal anterior-posterior development. To determine
盐细胞 chloride cell 存在于硬骨鱼类鳃上皮中的大形的嗜酸性分泌细胞，具有排出 NaCl的功能。细胞的基底部与血管相接，另端形成槽面朝向外界。在海产鱼类的鳃中这种细胞最多，淡水鱼则很少。若将鲑类（ salmo iride-us）和鳗等从淡水移至海水后，则这种细胞可急剧发达。细胞内有多量的线粒体，从基底部和侧面的细胞膜进入的小管以网眼状缠绕着线粒体，并面向端部。细胞内 Na－ K－ ATP酶的活性高，而皮质醇可增强盐细胞和酶的活性。拟枝额虫和无甲类 Artemia
Transepithelial Impedance Analysis of Chloride Secretion
Transepithelial chloride secretion requires the activation of both apical membrane chloride channels and basolateral membrane potassium channels. Chloride channels are needed for the apical membrane exit of chloride and potassium channels
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