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- 详细信息
- 技术资料
- 保存条件:
4°C, sealed storage, away from moisture
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
56293-29-9
- 规格:
10 mM * 1 mL/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥232.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥211.0 |
| 规格: | 50 mg | 产品价格: | ¥298.0 |
| 规格: | 100 mg | 产品价格: | ¥430.0 |
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Aloperine
CAS No. : 56293-29-9
MCE 国际站:Aloperine
产品活性:Aloperine 是一种在苦参类 (例如苦豆子 Sophora alopecuroides L) 植物中生物碱,其具有抗癌,抗炎和抗病毒特性。Aloperine 被广泛用于研究过敏性接触性皮炎湿疹和其他皮肤炎症。Aloperine 诱导 HL-60 细胞中诱导凋亡 apoptosis 和自噬 autophagy。
研究领域:Apoptosis | Autophagy | Anti-infection
作用靶点:Apoptosis | Autophagy | Filovirus | HIV
In Vitro: Aloperine (1-20 μM; 24 hours) gives growth-inhibitory IC50 values in cancer cells ranges from 0.04 to 1.36 mM, the IC50 values in HL-60, U937, K562, EC109, A549 and HepG2 cells are 0.04, 0.27, 0.36, 1.11, 1.18 and 1.36 mM,respectively.
Aloperine (1-20 μM; 24 hours) induces apoptosis and decreases bcl-2 expression in HL-60 cells.
Aloperine (20–100 μM; 18 hours) induces autophagy and formation of acidic vacuole in HL-60 cells.
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