Anastrozole(120511-73-1)(≥99%)

特别提示：包括Anastrozole在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：Anastrozole
英文名称：Anastrozole
产品货号：L10068
产品规格：1g|100mg|5g|500mg
 

属性

CAS号	120511-73-1
分子式	C17H19N5
分子量	293.37
溶解性	Soluble in chloroform,methanol,ethanol(59mg/ml at 25℃),DMSO(59mg/ml at 25℃),and DMF(~14 mg/ml).
存贮条件	储存温度-20℃

描述

产品介绍	Anastrozole is known to inhibit the CYP19 enzyme(aromatase,IC50 = 15 nM) that converts androgens to estrogens.Anastrozole has been seen to reversibly bind to the CYP19 enzyme through competitive inhibition.
备注	Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor.
生化机理	Anastrozole is a potent and highly selective aromatase(CYP19) inhibitor(IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis.Anastrozole reduces plasma estrogen levels and exhibits antitumor activity in vivo.Orally active.
别名	阿那曲唑;ICI-D1033;2;2"-[5-(1H-1;2;4-Triazol-1-ylmethyl)-1 3-Phenylene]bis(2-methyl-propiononitrile、Arimidex;ZD1033 a,a,a′,a′-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile

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