产品货号:jlcR3892 英文名称 :cGMP 中文名称 :环磷酸鸟苷抗体 别 名 :Cyclic GMP; Cyclic guanosine monophosphate; Guanosine 3 5 Cyclic Monophosphate. 产品类型 :药物与化合物抗体 研究领域 :肿瘤 细胞生物 免疫学 染色质和核信号 信号转导 转录调节因子 药物及化合物 抗体来源 :Rabbit 克隆类型 :Polyclonal 交叉反应 :cGMP,cGMP,cGMP 产品应用 :ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :0.34521kDa 性 状 :Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated cGMP: 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 : Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
SWISS: N/A
CAS: 7665-99-8
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.