murine TCR OTI-2A.pMIG II Plas

T-Cell Cytotoxicity Assays for Studying the Functional Interaction Between the Superantigen Staphylococcal Enterotoxin A and T-Cell Receptors

lymphocytes (1 ,2 ). T-cell activation induced by SEs involves binding to constant parts of major histocompatibility complex (MHC) class II molecules and subsequent interaction with T cells expressing certain T-cell receptor (TCR) Vβ chains

Production and Characterization of Receptor-Specific TNF Muteins

method for the introduction of a specific mutation in mature murine TNF making use of double-stranded plasmid DNA and two oligonucleotides. Two in vitro protocols are given that allow assessment of the binding of wild-type TNF and/or TNF muteins to TNF

Identification of T-Cell Epitopes

with major histocompatibility complex (MHC) antigens. Peptides bound to Class I or Class II MHC proteins are recognized, at the surface of an antigen-presenting cell (APC), by T-cells carrying the CD8 or CD4 molecules, respectively. Recognition through the T-cell receptor (TCR