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100 µL
抗体种属:Human
抗体靶点:CYP3A4
抗体应用:IHC-P
抗原货号:0
抗原描述:A synthetic peptide corresponding to the C-terminus of the Human CYP3A4 / Cytochrome P450 3A4
抗体宿主:Rabbit
抗体Ig类型:Rabbit IgG
抗体纯化方法:Protein A & Antigen Affinity
抗体制备:Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human CYP3A4 / Cytochrome P450 3A4, and purified by antigen affinity chromatography.
抗体特异性:Human CYP3A4 / Cytochrome P450 3A4
抗体保存:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
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文献和实验Cytochrome P450 Reconstitution Systems
Human liver microsomes contain multiple forms of cytochrome P450 (CYP or P450) that catalyze oxidation of a number of xenobiotic and endobiotic chemicals. Individual P450 forms have unique, but overlapping, substrate specificities
Evaluation of Cytochrome P450 Activities in Human Hepatocytes In Vitro
Major hepatic cytochrome P450 activities (CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4) can be simultaneously examined in human hepatocytes by incubation with a cocktail of multiple specific probes. Cocktail strategy
Assessment of CYP3A4 Time-Dependent Inhibition in Plated and Suspended Human Hepatocytes
This chapter provides a step-by-step description of methodology used to assess time-dependent inhibition/inactivation (TDI) potential of cytochrome P450 3A4 (CYP3A4) by a test compound using human hepatocytes in a 96-well plate format. Human
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