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- 详细信息
- 文献和实验
- 技术资料
- 库存:
450
- 英文名:
Recombinant Murine Interleukin-16
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冷冻(-20℃)
- 规格:
2μg
特别提示:包括重组小鼠IL-16(121a.a.)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组小鼠IL-16(121a.a.)
英文名称:Recombinant Murine Interleukin-16
产品货号:GS4561
产品规格:2μg
分子量:Approximately 12.2kDa,a single non-glycosylated polypeptide chain containing 118 amino acids.
储存条件:冷冻(-20℃)
概述
Interleukin-16(IL-16)is also called lymphocyte chemoattractant factor(LCF)and it is mostly secreted by lymphocytes,epithelial cells,eosinophils,and CD8+ T cells.It has many functions including induction of the IL-2Rα on T cells,suppression of human immunodeficiency virus(HIV)replication,inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on.It signals through CD4 receptor.Furthermore,recombinant murine interleukin-16 contains 118 amino acid residues and it shares about 85%a.a.sequence identity with different isoforms of human IL-16.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | >98%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rMuIL-16 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SAASASAASD ISVESKEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFKGTEQ GEMVQPGDEI LQLAGTAVQG LTRFEAWNVI KALPDGPVTI VIRRTSLQCK QTTASADS |
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文献和实验相关实验
的IL-1Rt I(CD121a)、IL-1RtⅡ(CD121b)、IL-6Rα链(CD126)、gp130(CDw130)、G-CSFR、M-CSFR(CD115)、SCFR(CD117)和PDGFR,并可分为几种不同的结构类型,不同IGSF结构类型的受体其信号转导途径也有差别。 (1)M-CSFR、SCFR和PDGFR:胞膜外区均含有5个Ig样结构域,其中靠近胞膜区为1个V样结构,其余4个为C2样结构。受体通常以二聚体形式与相应的同源二聚体配体结合。受体胞浆区本身含有蛋白酷氨
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重组小鼠IL-16(121a.a.)报价
¥380 - 3800









