- ￥2890
- LSM Bio
- 参照说明书
- 0.31-20ng/ml
- 国产
- ELI-08527h
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
50
- 供应商：
LSMBIO
- 检测范围：
参照说明书
- 检测方法：
夹心法/竞争法
- 应用：
0.1ng/ml
- 适应物种：
人
- 标记物：
Microtubule- associated protein 1B, MAP1B
- 样本：
人血清、血浆或其它相关生物液体中天然和重组蛋白
- 灵敏度：
0.31-20ng/ml
- 规格：
96T
Human Microtubule- associated protein 1B, MAP1B ELISA KIT
Product Name:Human Microtubule- associated protein 1B, MAP1B ELISA KIT
Packing:96T
Catalog No.:ELI-08527h
Gene Name:MAP1B
Detect Range:78-5000 pg/mL
Sensitivity:32pg/mL
Target Protein Name:Microtubule-associated protein 1B(MAP1B
Alternative Name:MAP1B,Microtubule-associated protein 1B(MAP1B
Sample type:serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
ELISA type:Sandwich ELISA Kit
Product Description:Human Microtubule- associated protein 1B, MAP1B ELISA KIT allows for the in vitro quantitative determination of Microtubule-associated protein 1B(MAP1B concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
ELISA Test Principle:
The microtiter plate provided in Human Microtubule- associated protein 1B, MAP1B ELISA KIT has been pre-coated with an Microtubule-associated protein 1B(MAP1B antibody specific to Microtubule-associated protein 1B(MAP1B .Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for Microtubule-associated protein 1B(MAP1B and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain Microtubule-associated protein 1B(MAP1B, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm.The concentration of Microtubule-associated protein 1B(MAP1B in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NOTE:FOR RESEARCH USE ONLY; NOT FOR THERAPEUTIC OR DIAGNOSTIC APPLICATIONS! PLEASE READ ENTIRE PROCEDURE!
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文献和实验微管结合蛋白(microtubule-associated proteins, MAPs)
与微管特异地结合在一起, 对微管的功能起辅助作用的蛋白质称为微管结合蛋白, 在微管结构中约占10～15%。 一类主要的MAPs家族叫作装配MAPs(assembly MAPs), 作用是将微管在胞质溶胶中进行交联。这些MAPs的结构中具有两个结构域, 一个是碱性的微管蛋白结合结构域, 另一个是酸性的外伸的结构域。 根据序列特点, 将MAPs分成两个主要的类型:Ⅰ型和Ⅱ型(还有其他类型)。MAP1A和MAP1B含有几个重复的氨基酸序列:Lys-Lys-Glu
Screening for Inhibitors of Microtubule-Associated Motor Proteins
The mitotic spindle is an important target for cancer chemotherapy. The main protein target for drugs in clinical use is tubulin, the building block of microtubules. In recent years, other proteins of the mitotic spindle have been identified
is essential. A variety of microtubule-associated proteins (MAPs), including MAP2, MAP1B, and tau, regulating growth and stability of microtubules, are present in oligodendrocytes, and also the myelin-specific proteins MBP and CNP associate with microtubules
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