重组人BMP-2北京供应商

特别提示：包括重组人BMP-2在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人BMP-2
英文名称：Recombinant Human Bone Morphogenetic Protein 2
产品货号：GS4400
产品规格：2μg

分子量：Approximately 26.0kDa,a homodimeric protein consisting of two 115 amino acid non-glycosylated polypeptide chains.
储存条件：冷冻（-20℃）

概述

Bone Morphogenetic Protein 2 is one of the BMPs,some of which belong to the TGF-beta superfamily(BMP2-7).There are more than thirteen BMPs have been discovered nowadays and they are involved in inducing cartilage and bone formation.BMP-2 is expressed in a variety of tissues including lung,spleen,brain,liver,prostate ovary and small intestine.It is a potent osteoinductive cytokine and plays its role in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite.As it shown to stimulate the production of bone,the recombinant human BMP-2 is available for orthopaedic usage and dentisty.The functional form of BMP-2 is a disulflde-linked homodimer and about 26 kDa The precursor of BMP-2 is 259 a.a.,containing the 23 a.a.N-terminal signal sequence which will be cleaved by a furin-type protease to form the mature peptide.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 200ng/ml,corresponding to a specific activity of>5.0×103 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution containing 10mMsodium citrate pH 3.5.
内毒素	Less than 1 EU/μg of rHuBMP-2 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled H2O to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.Do not reconstitute in PBS or cell culture media.
氨基酸序列	MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

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