- ￥2860
- LSM Bio
- 进口
- PAab09573
- 2025年07月08日
- ELISA,WB,IF,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
YTH domain family, member 2
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
O95498
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IF,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
YTH domain family, member 2
- 抗体英文名：
anti-YTHDF2 antibody,YTHDF2 antibody
- 抗体名：
anti-YTHDF2 抗体,YTHDF2 抗体
- 规格：
100μl
YTHDF2抗体| YTHDF2 antibody
货号 PAab09573
蛋白别名 CLL associated antigen KW 14 antibody, HGRG8 antibody, NY REN 2 antibody, YTH domain family protein 2 antibody, YTH domain family antibody, member 2 antibody, YTHDF2
蛋白介绍
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:22575960, PubMed:24284625, PubMed:25412658, PubMed:25412661). Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P- bodies), leading to mRNA degradation (PubMed:24284625, PubMed:26046440). Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation (PubMed:26458103).
产品描述
anti-YTHDF2 antibody is a Rabbit Polyclonal antibody againstYTHDF2..
建议稀释比例
WB:1:500-1:5000;IF:1:10-1:100;IP:1:200-1:2000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human testis tissue slide using PAab09573( YTHDF2 Antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09573( YTHDF2 Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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