- ￥2262
- LSM Bio
- 进口
- PAab06430
- 2025年07月16日
- ELISA,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
protein inhibitor of activated STAT, 3
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
protein inhibitor of activated STAT, 3
- 抗体英文名：
anti-PIAS3 antibody,PIAS3 antibody
- 抗体名：
anti-PIAS3 抗体,PIAS3 抗体
- 规格：
100μg
PIAS3抗体| PIAS3 antibody
货号 PAab06430
蛋白别名
蛋白介绍
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation (PubMed:21965678, PubMed:9388184). Sumoylates CCAR2 which promotes its interaction with SIRT1 (PubMed:25406032). Diminishes the sumoylation of ZFHX3 by preventing the colocalization of ZFHX3 with SUMO1 in the nucleus (PubMed:24651376).
产品描述
anti-PIAS3 antibody is a Rabbit Polyclonal antibody againstPIAS3..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验, GAB2, GNG2, GRB2, HRAS, INDO, KRAS2, KSR, MADH1, MADH2, MADH3, MADH4, MADH5, MADH6, MADH7, MADH9, MAPK8IP1, MCM5, MIZ1, NRAS, OSM, PAK1, PAK3, PIAS1, PIAS3, PIASY, PIM1, PREX1, PTPN1, PTPNS1, PTPRC, RAC1, RAC2, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS
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