- ￥2260
- LSM Bio
- 进口
- PAab09196
- 2025年07月08日
- ELISA,IHC,WB,IF
- E. coli - derived recombinant protein
- Human,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
ubiquilin 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,WB,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
ubiquilin 1
- 抗体英文名：
anti-Ubiquilin 1 antibody,Ubiquilin 1 antibody
- 抗体名：
anti-Ubiquilin 1 抗体,Ubiquilin 1 抗体
- 规格：
100μl
Ubiquilin 1抗体| Ubiquilin 1 antibody
货号 PAab09196
蛋白别名 DA41 antibody, DSK2 antibody, FLJ90054 antibody, hPLIC 1 antibody, PLIC 1 antibody, PLIC1 antibody, ubiquilin 1 antibody, UBQLN1 antibody, XDRP1
蛋白介绍
UBQLN1, also known as DSK2 or Ubiquilin 1, is an ubiquitin-like proteinis contains a?N-terminal?ubiquitin-like?domain?and a C-terminal ubiquitin-associated domain.?They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation.Ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with?Alzheimer's?and?Parkinson's?disease. Two transcript variants encoding different isoforms have been found for this gene. Higher levels of ubiquilin-1 in the brain decreased malformation of the APP molecule which plays a key role in triggering Alzheimers disease.Conversely, lower levels of ubiquilin-1 in the brain were associated with increased malformation of APP?(PMID: 21852239). This antibody detects 70kD band of UBQLN1.
产品描述
anti-Ubiquilin 1 antibody is a Rabbit Polyclonal antibody againstUbiquilin 1..
建议稀释比例
WB : 1:200-1:1000;IF:1:10-1:100;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human pancreas slide using PAab09196( UBQLN1 Antibody) at dilution of 1:50
Western blot
rat brain tissue were subjected to SDS PAGE followed by western blot with PAab09196( Ubiquilin 1 Antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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